The contribution of cytosolic enzymes to xenobioticmetabolism may be remarkable in extrahepatic tissues.
2
Mothers and children shared variation in xenobioticmetabolism genes.
3
The enzyme was unable to hydrolyze 4-nitrophenyl sulfate, suggesting its role in xenobioticmetabolism does not extend beyond phosphates.
4
One important class of biological reactive intermediates arising in the course of human xenobioticmetabolism are arene and alkene oxides.
5
In addition, a new study reveals the mutual repression between PXR and NF-kappaB signaling pathways, providing a molecular mechanism linking xenobioticmetabolism and inflammation.
Ús de drug metabolism en anglès
1
A2780 ovarian cells neither catalysed drugmetabolism nor contained these drug transporters.
2
During the inflammatory response, intrahepatic cholestasis and decreased drugmetabolism are frequently observed.
3
CCRP appears to be involved in various hepatic regulations far beyond CAR-mediated drugmetabolism.
4
Expression data were compared to changes in conventional clinical chemistry parameters and drugmetabolism activities.
5
Genetic variation in genes encoding cytochrome P450 enzymes has important clinical implications for drugmetabolism.
6
Here, we extend our analysis to drugmetabolism enzymes.
7
A model to study hepatic and intestinal drugmetabolism in the dog has been evaluated.
8
However, the inhibition of drugmetabolism in DTP vaccine-treated mice was similar in all three groups.
9
However, HF-iPS efficiently induced the generation of HLCs that expressed hepatocyte markers and drugmetabolism-related genes.
10
Additionally, it has long been appreciated that exposure to drugmetabolism-inducing xenobiotics can impair immune function.
11
After chronic intramuscular administration FK inhibits drugmetabolism.
12
O'Malley was the first researcher to write a paper on the effect of ageing on drugmetabolism.
13
Enzymes involved in drugmetabolism are genetically polymorphic, meaning that their activities differ depending on certain genotypes.
14
Primary human hepatocytes (PHHs) are an essential tool for modeling drugmetabolism and liver disease.
15
Tumors were analyzed for mRNA expression and polymorphisms in genes involved in drugmetabolism and DNA repair.
16
Conversely, little is known about the role of this pathway in drugmetabolism regulation in human liver.